P005145 revised AU-VU:EOAS Encyclopedia of Australian Science and Innovation

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 English AACR2 Anglo-American Cataloguing Rules Person created 2012-06-13 human Rebecca rigby updated 2024-04-23 human https://www.eoas.info/biogs/P005145b.htm person Varghese Joseph Noozhumurry AACR2 13 March 1949 Place of Birth Nairobi, Kenya Virologist Molecular biologist Jose Varghese is an expert molecular biologist who has worked in the medical research field since 1980 when was invited by Peter Colman to collaborate on analysis of human influenza Type A viruses in 1980. This research had unprecedented results in terms of identifying the structure of the virus and allowed for the development of Relenza, a groundbreaking drug that works against all strains of influenza virus including bird flu and swine flu. When he was seconded from his position with Colman in the CSIRO's Division of Protein Chemistry, to the Biomolecular Research Institute, Varghese continued his research into influenza. During his time there (1990-2000) he also led successful research into the following; the structure of several plant hydrolyses; the structure of the Interleukin-6 receptor; the improvement of X-Ray brilliance using mono-capillary optics; the construction of computer simulations molecules binding onto a protein surface to aid the process of drug design. Varghese has published over 90 scientific articles, which have been cited, as of 2008, over 4 600 times.

In 2011 Varghese (with colleagues in the Amyloid Structure Team) was awarded the CSIRO Medal for Research Achievement for determining one of the first known structures of amyloid beta - a toxic protein present in the brains of Alzheimer's sufferers. The structure has been sought for 25 years, but had proved incredibly difficult because of the protein's propensity to self-assemble and clump together.

1968 1968 Education - Bachelor of Science (Physics and Mathematics), University of Queensland 1969 1969 Education - Honours in Theoretical Physics, University of Queensland 1970 1974 Education - Doctor of Philosophy (PhD) in Physics, University of Western Australia at Nedlands, Perth 1974 c. 1977 Career position - ARC Postdoctoral Fellowship at the Crystallography Centre, University of Western Australia 1977 c. 1980 Career position - Science Research Council (UK) Postdoctoral Fellowship at the School of Molecular Sciences, University of Sussex in England 1980 c. 1984 Career position - CSIRO Postdoctoral Fellowship with Dr Peter Colman, CSIRO Division of Protein Chemistry 1984 1990 Career position - Principal Research Scientist, CSIRO Biomolecular Engineering 1987 1987 Award - CSIRO Medal for Research Achievement (with colleagues) 1990 2000 Career position - Chief Research Scientist, Biomolecular Research Institute, Parkville 2001 2005 Career position - Head, Structural Biology Program CSIRO Health Sciences and Nutrition CSIRO Division of Biomolecular Engineering, Commonwealth Scientific and Industrial Research Organisation (1989 - 1997)

Principal Research Scientist 1984 - 1990

 CSIRO Medal for Research Achievement (1985 - )

Awarded the Medal (with colleagues) 2011

 Varghese, Joseph Noozhumurry (19490313-)

Trove

 'Varghese, Joseph Noozhumurry (Jose)', in Encyclopedia of Australian Science and Innovation, Centre for Transformative Innovation, Swinburne University of Technology Varghese, Joseph Noozhumurry (Jose) Swinburne University of Technology, Centre for Transformative Innovation Encyclopedia of Australian Science and Innovation Resource Section: Joseph Noozhumurry (Jose) Varghese Ward, C. Joseph Noozhumurry (Jose) Varghese Commonwealth Scientific and Industrial Research Organisation (CSIRO) 2011 CSIROpedia Commonwealth Scientific and Industrial Research Organisation (CSIRO) Resource Section: CSIRO Entrepreneurship Award Ward, Colin CSIRO Entrepreneurship Award Commonwealth Scientific and Industrial Research Organisation (CSIRO) 2013 CSIROpedia Commonwealth Scientific and Industrial Research Organisation (CSIRO)